Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004187 | 0.84 | ALOX15 (0.67) | TSHRALDH1A1RXFP1KMT2AMEN1 | |
| SCHEMBL6003781 | 0.79 | NPY5R (0.49) | TSHRALDH1A1RXFP1KMT2AKDM4E | |
| SCHEMBL17664366 | 0.71 | GRIK1 (0.58) | ALDH1A1RXFP1KMT2ATMPRSS4MEN1 | |
| SCHEMBL17664372 | 0.70 | RXFP1 (0.58) | ALDH1A1RXFP1KMT2AMEN1MAPT | |
| SCHEMBL6004189 | 0.70 | ALOX15 (0.66) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL17664277 | 0.70 | MAPT (0.59) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL16008793 | 0.69 | GRIK1 (0.58) | KMT2AMEN1MAPT | |
| SCHEMBL13561074 | 0.69 | KMT2A (0.72) | TSHRALDH1A1KMT2ATMPRSS4MEN1 | |
| SCHEMBL17664311 | 0.69 | P2RX1 (0.66) | RXFP1KMT2ATMPRSS4MEN1SLC2A1 | |
| SCHEMBL6522071 | 0.69 | NPC1 (0.53) | ALDH1A1KMT2AKDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | TSHR 1521/4885ALDH1A1 763/4885RXFP1 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.