SCHEMBL600664

SCHEMBL600664

COc1cc(Nc2cccc(N(C)C)c2)ccc1N

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EGFR P00533 4/20 0.45
JAK2 O60674 2/20 0.44
FLT3 P36888 1/20 0.44
ERBB2 P04626 1/20 0.44
KDM1A O60341 1/20 0.43
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
APP P05067 2/20 0.42
ACP1 P24666 1/20 0.40
FYN P06241 4/20 0.38
MAPK14 Q16539 1/20 0.38
JAK1 P23458 1/20 0.38
TYK2 P29597 1/20 0.38
JAK3 P52333 1/20 0.38
NTRK1 P04629 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29837453 0.81 ALDH1A1 (0.50) FLT3ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL1639956 0.81 ALDH1A1 (0.50) FLT3ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL599074 0.80 ALDH1A1 (0.54) EGFRJAK2KDM1AALDH1A1CYP3A4
SCHEMBL30236 0.79 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRHSD17B10TDP1
SCHEMBL29763986 0.79 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRHSD17B10TDP1
SCHEMBL600071 0.79 KDM1A (0.44) EGFRJAK2KDM1AALDH1A1CYP3A4
SCHEMBL3030672 0.79 KDM1A (0.59) EGFRJAK2KDM1AALDH1A1TSHR
SCHEMBL9649012 0.78 ALDH1A1 (0.53) EGFRJAK2KDM1AALDH1A1CYP3A4
SCHEMBL2739262 0.77 ALDH1A1 (0.59) ALDH1A1CYP3A4TSHRHSD17B10TDP1
SCHEMBL6996659 0.76 ALDH1A1 (0.51) EGFRJAK2FLT3ERBB2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230027721-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2023-01-26 US disclosed
EP-3351398-A1 HEAT-SENSITIVE RECORDING BODY Nippon Paper Industries Co., Ltd. (JP) 2018-07-25 EP disclosed
US-20160236497-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2016-08-18 US disclosed
US-8871678-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-10-28 US disclosed
US-8722576-B2 Thermosensitive recording label NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-05-13 US disclosed
US-8673812-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-03-18 US disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8466085-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-06-18 US disclosed
US-20130059728-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-03-07 US disclosed
US-8283284-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-10-09 US disclosed
US-20120208698-A1 THERMOSENSITIVE RECORDING LABEL NIPPON PAPER INDUSTRIES CO., LTD 2012-08-16 US disclosed
US-20120129692-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-05-24 US disclosed
US-20120038737-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-02-16 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
US-20110105319-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-05-05 US disclosed
US-20100248959-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-09-30 US disclosed