SCHEMBL599074

SCHEMBL599074

Cc1cc(Nc2cccc(N(C)C)c2)ccc1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TDP1 Q9NUW8 3/20 0.54
CYP3A4 P08684 2/20 0.54
ALOX15 P16050 2/20 0.54
THRB P10828 1/20 0.54
RECQL P46063 1/20 0.54
HIF1A Q16665 1/20 0.54
KDM1A O60341 1/20 0.46
EGFR P00533 1/20 0.44
JAK2 O60674 1/20 0.40
JAK1 P23458 1/20 0.40
TYK2 P29597 1/20 0.40
JAK3 P52333 1/20 0.40
APAF1 O14727 1/20 0.40
NOS1 P29475 1/20 0.39
BTK Q06187 1/20 0.39
RAPGEF4 Q8WZA2 1/20 0.38
TSHR P16473 2/20 0.38
MAPT P10636 2/20 0.38
S100B P04271 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL600071 0.83 KDM1A (0.44) ALDH1A1TDP1CYP3A4ALOX15KDM1A
SCHEMBL3030672 0.82 KDM1A (0.59) ALDH1A1ALOX15KDM1AEGFRJAK2
SCHEMBL9649012 0.81 ALDH1A1 (0.53) ALDH1A1TDP1CYP3A4ALOX15KDM1A
SCHEMBL11511767 0.80 CYP3A4 (0.77) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL600664 0.80 EGFR (0.45) ALDH1A1TDP1CYP3A4KDM1AEGFR
SCHEMBL3792803 0.80 CYP3A4 (0.61) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL30998047 0.79 ALDH1A1 (0.70) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL2127369 0.79 ALDH1A1 (0.70) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL28557487 0.77 KDM1A (0.63) ALDH1A1TDP1CYP3A4ALOX15KDM1A
SCHEMBL29709 0.77 CYP3A4 (0.71) ALDH1A1TDP1CYP3A4ALOX15THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4093285-A None JP disclosed
US-8871678-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-10-28 US disclosed
US-8722576-B2 Thermosensitive recording label NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-05-13 US disclosed
US-8673812-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-03-18 US disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8466085-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-06-18 US disclosed
US-20130059728-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-03-07 US disclosed
US-20120208698-A1 THERMOSENSITIVE RECORDING LABEL NIPPON PAPER INDUSTRIES CO., LTD 2012-08-16 US disclosed
US-20120129692-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-05-24 US disclosed
US-20120038737-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-02-16 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
US-20100248959-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-09-30 US disclosed
EP-1115579-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION Ciba SC Holding AG (CH) 2001-07-18 EP disclosed
WO-2000012318-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed
JP-H0493285-A THERMAL RECORDING CARD JUJO PAPER CO LTD 1992-03-26 JP disclosed