SCHEMBL600071

SCHEMBL600071

CN(C)c1cccc(Nc2ccc(N)c(Cl)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.44
EGFR P00533 1/20 0.43
ACP1 P24666 1/20 0.40
JAK2 O60674 1/20 0.39
JAK1 P23458 1/20 0.39
TYK2 P29597 1/20 0.39
JAK3 P52333 1/20 0.39
NOS1 P29475 1/20 0.39
MAPT P10636 4/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
TSHR P16473 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 2/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599074 0.83 ALDH1A1 (0.54) KDM1AEGFRJAK2JAK1TYK2
SCHEMBL3030672 0.81 KDM1A (0.59) KDM1AEGFRACP1JAK2JAK1
SCHEMBL9649012 0.80 ALDH1A1 (0.53) KDM1AEGFRJAK2JAK1TYK2
SCHEMBL11593134 0.79 CYP3A4 (0.54) TSHRSMN1; SMN2ALDH1A1CYP3A4GAA
SCHEMBL600664 0.79 EGFR (0.45) KDM1AEGFRACP1JAK2JAK1
SCHEMBL28557487 0.76 KDM1A (0.63) KDM1AEGFRACP1MAPTMEN1
SCHEMBL3780601 0.75 TSHR (0.50) KMT2ATSHRSMN1; SMN2TP53ALDH1A1
SCHEMBL29793623 0.75 TSHR (0.50) KMT2ATSHRSMN1; SMN2TP53ALDH1A1
SCHEMBL18334947 0.73 CYP3A4 (0.49) MAPTMEN1KMT2ATSHRSMN1; SMN2
SCHEMBL10571080 0.70 KDM1A (0.53) KDM1AEGFRACP1JAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160236497-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2016-08-18 US disclosed
US-8871678-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-10-28 US disclosed
US-8722576-B2 Thermosensitive recording label NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-05-13 US disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8466085-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-06-18 US disclosed
US-20130059728-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-03-07 US disclosed
US-8283284-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-10-09 US disclosed
US-20120208698-A1 THERMOSENSITIVE RECORDING LABEL NIPPON PAPER INDUSTRIES CO., LTD 2012-08-16 US disclosed
US-20120038737-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-02-16 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
US-20110105319-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-05-05 US disclosed
US-20100248959-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-09-30 US disclosed