SCHEMBL600668

SCHEMBL600668

c1cnc2c(c1)ccc1cnncc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.60
CCR8 P51685 5/20 0.60
LMNA P02545 3/20 0.60
CCR5 P51681 3/20 0.60
MMP2 P08253 2/20 0.60
TSHR P16473 2/20 0.60
KDM4E B2RXH2 2/20 0.60
MAPT P10636 2/20 0.60
CYP3A4 P08684 2/20 0.60
GMNN O75496 1/20 0.60
TP53 P04637 1/20 0.60
HSP90AA1 P07900 1/20 0.60
CYP2D6 P10635 1/20 0.60
MMP9 P14780 1/20 0.60
ALOX15 P16050 1/20 0.60
NFKB1 P19838 1/20 0.60
MMP8 P22894 1/20 0.60
THPO P40225 1/20 0.60
MTOR P42345 1/20 0.60
HTT P42858 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1246514 0.80 CCR1 (0.75) CCR1CCR8LMNACCR5MMP2
Phenanthroline SCHEMBL27885493 0.79 CCR1 (0.94) CCR1CCR8LMNACCR5MMP2
Phenanthroline SCHEMBL29635370 0.79 CCR1 (0.94) CCR1CCR8LMNACCR5MMP2
SCHEMBL1419171 0.78 LMNA (0.58) CCR1CCR8LMNACCR5MMP2
SCHEMBL1419145 0.78 LMNA (0.58) CCR1CCR8LMNACCR5MMP2
Phenanthroline SCHEMBL29354015 0.77 CCR1 (1.00) CCR1CCR8LMNACCR5MMP2
Phenanthroline SCHEMBL29367277 0.77 CCR1 (1.00) CCR1CCR8LMNACCR5MMP2
Phenanthroline SCHEMBL8312 0.77 CCR1 (1.00) CCR1CCR8LMNACCR5MMP2
Phenanthroline SCHEMBL8845760 0.77 CCR1 (1.00) CCR1CCR8LMNACCR5MMP2
Water SCHEMBL14697038 0.76 LMNA (0.56) CCR1CCR8LMNACCR5MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9947877-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2018-04-17 US disclosed
US-9947877-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2018-04-17 US disclosed
US-20160285010-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-09-29 US disclosed
US-8329898-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2012-12-11 US disclosed
US-20120041197-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These NOVALED AG (DE) 2012-02-16 US disclosed
US-8115003-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2012-02-14 US disclosed
US-20110046374-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These NOVALED AG (DE) 2011-02-24 US disclosed
US-7807687-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2010-10-05 US disclosed
EP-1970371-B1 Pyrido(3,2-h)chinazolins and/or 5,6-Dihydro derivatives thereof, method for their manufacture and endowed organic semiconductor material containing them NOVALED AG (DE) 2010-08-25 EP disclosed
US-20080227979-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2008-09-18 US disclosed
EP-1970371-A1 Pyrido(3,2-h)chinazolins and/or 5,6-Dihydro derivatives thereof, method for their manufacture and endowed organic semiconductor material containing them Novaled AG (DE) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041197-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These PDXK, PNPO, QDPR CCR1 4133/4885CCR8 3552/4885LMNA 3892/4885
US-20080227979-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these PDXK, PNPO, QDPR CCR1 4133/4885CCR8 3552/4885LMNA 3892/4885
US-20110046374-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These PDXK, PNPO, QDPR CCR1 4133/4885CCR8 3552/4885LMNA 3892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.