Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27854439 | 0.85 | ABCB1 (0.63) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL25798793 | 0.81 | ABCB1 (0.62) | CALM1ABCB1CNR2HTR1A | |
| SCHEMBL27606503 | 0.80 | CALM1 (0.44) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL14243461 | 0.80 | CALM1 (0.59) | CALM1TTR | |
| SCHEMBL621779 | 0.80 | HTR1A (0.58) | IDO1ABCB1HTR1AADRA1DADRA1A | |
| SCHEMBL9147925 | 0.79 | HSP90AB1 (0.44) | TTR | |
| SCHEMBL27502952 | 0.78 | MRGPRX4 (0.66) | — | |
| SCHEMBL3455690 | 0.78 | BCHE (0.70) | BCHEHTR2AHTR2C | |
| SCHEMBL29098359 | 0.78 | ALOX5 (0.61) | — | |
| SCHEMBL5801725 | 0.78 | ALOX5 (0.56) | TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706442-A1 | PROTON-CONDUCTING MEMBRANE AND USE THEREOF | Pemeas GmbH (DE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005063852-A1 | PROTON-CONDUCTING MEMBRANE AND USE THEREOF | PEMEAS GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |