Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 4/20 | 0.53 |
| ▸ | CTSG | P08311 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098359 | 0.86 | ALOX5 (0.61) | ALOX5ELANECTSGBCL2BCL2L1 | |
| SCHEMBL343656 | 0.86 | ALOX5 (0.59) | ALOX5ELANEBCL2BCL2L1F2 | |
| SCHEMBL31555136 | 0.85 | ABCB1 (0.58) | — | |
| SCHEMBL7283988 | 0.85 | CALM1 (0.50) | CYP19A1 | |
| SCHEMBL2090122 | 0.82 | CA2 (0.57) | — | |
| SCHEMBL29066049 | 0.81 | TUBB4A (0.59) | — | |
| SCHEMBL30297719 | 0.81 | ALOX5 (0.54) | ALOX5ELANECTSGBCL2BCL2L1 | |
| SCHEMBL4512063 | 0.81 | ALOX5 (0.50) | ALOX5ELANECTSGF2 | |
| SCHEMBL3958050 | 0.81 | GPR55 (0.50) | — | |
| SCHEMBL11288852 | 0.81 | LTA4H (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073744-A | Novel heterocyclic compounds as bromodomain inhibitors | RVX THERAPEUTICS INC | 2015-11-18 | — | — | CN | claimed |
| WO-2006077483-A2 | METHOD FOR THE PRODUCTION OF ALKOXY-SUBSTITUTED PHENOLS | MERISOL RSA (PTY) LTD (ZA) | 2006-07-27 | — | — | WO | claimed |
| CN-105073744-B | Novel heterocyclic compounds as bromine structural domain inhibitor | ZENITH EPIGENETICS CORP. (CA) | 2019-11-08 | — | — | CN | disclosed |
| CN-105073744-A | Novel heterocyclic compounds as bromodomain inhibitors | RVX THERAPEUTICS INC | 2015-11-18 | — | — | CN | disclosed |
| WO-2006077483-A3 | METHOD FOR THE PRODUCTION OF ALKOXY-SUBSTITUTED PHENOLS | MERISOL RSA PTY LTD (ZA) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006077483-A2 | METHOD FOR THE PRODUCTION OF ALKOXY-SUBSTITUTED PHENOLS | MERISOL RSA (PTY) LTD (ZA) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006077483-A2 | METHOD FOR THE PRODUCTION OF ALKOXY-SUBSTITUTED PHENOLS | MERISOL RSA (PTY) LTD (ZA) | 2006-07-27 | — | — | WO | disclosed |