Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358295 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4LMNAAOC3ALDH1A1 | |
| SCHEMBL6807357 | 0.85 | SLC6A2 (0.47) | SLC6A2SLC6A4LMNAAOC3ALDH1A1 | |
| SCHEMBL4352146 | 0.81 | ALDH1A1 (0.44) | SLC6A2SLC6A4ALDH1A1TSHRKDM4E | |
| SCHEMBL3402708 | 0.80 | LMNA (0.52) | SLC6A2SLC6A4LMNAAOC3ALDH1A1 | |
| SCHEMBL1408150 | 0.80 | LMNA (0.46) | SLC6A2SLC6A4LMNAAOC3ALDH1A1 | |
| SCHEMBL21480202 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4LMNAAOC3ALDH1A1 | |
| SCHEMBL7328519 | 0.79 | CHRM5 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL9446189 | 0.79 | SLC6A2 (0.50) | SLC6A2SLC6A4LMNAALDH1A1GLA | |
| Alcohol SCHEMBL14920530 | 0.78 | L3MBTL1 (0.39) | SLC6A2SLC6A4LMNAALDH1A1KDM4E | |
| SCHEMBL22431416 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4AOC3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1704138-A1 | PROCESSES FOR THE PREPARATION OF TOMOXETINE | Teva Pharmaceutical Fine Chemicals S.R.L. (IT) | 2006-09-27 | — | — | EP | disclosed |
| WO-2006068662-A1 | PROCESSES FOR THE PREPARATION OF TOMOXETINE | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2006-06-29 | — | — | WO | disclosed |