Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007228 | 0.78 | SLC6A2 (0.49) | L3MBTL1KDM4ESLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL7524554 | 0.78 | L3MBTL1 (0.46) | L3MBTL1CYBBNOX4KDM4EPPARG | |
| SCHEMBL14920406 | 0.78 | ALDH1A1 (0.48) | L3MBTL1CYBBNOX4KDM4EALDH1A1 | |
| SCHEMBL4358295 | 0.78 | SLC6A2 (0.49) | L3MBTL1KDM4ESLC6A2SLC6A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11398990 | 0.76 | L3MBTL1 (0.46) | L3MBTL1CYBBNOX4KDM4EPPARG | |
| SCHEMBL9755649 | 0.73 | OPRM1 (0.47) | L3MBTL1CYBBNOX4KDM4EPPARG | |
| SCHEMBL9436565 | 0.71 | OPRM1 (0.46) | L3MBTL1CYBBNOX4KDM4EPPARG | |
| SCHEMBL3038423 | 0.71 | OPRM1 (0.46) | L3MBTL1CYBBNOX4KDM4EPPARG | |
| 1,4-Butanediol SCHEMBL3216941 | 0.71 | RAB9A (0.47) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| Alcohol SCHEMBL2682103 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773378-A1 | PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS) | Larsen, Claus Selch (DK) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064153-A1 | PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2013-05-10 | — | — | WO | disclosed |