Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009354 | 0.91 | KCNH2 (0.61) | KCNH2S1PR5KDM2BHSD11B1SLC6A4 | |
| SCHEMBL6007927 | 0.91 | KCNH2 (0.57) | KCNH2HTR2AS1PR5KDM2BHSD11B1 | |
| SCHEMBL6009253 | 0.89 | KCNH2 (0.55) | KCNH2HTR2AS1PR5CHRM2CHRM3 | |
| SCHEMBL6009245 | 0.88 | MGLL (0.54) | KCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL6007356 | 0.86 | HTR2A (0.61) | KCNH2HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6007909 | 0.83 | MGLL (0.54) | KCNH2HTR2A | |
| SCHEMBL3838692 | 0.83 | HTR2A (0.61) | HTR2ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL3838687 | 0.83 | HTR2A (0.61) | HTR2ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL3838690 | 0.83 | HTR2A (0.61) | HTR2ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL9647537 | 0.81 | HTR2A (0.72) | KCNH2HTR2AKDM2BHTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | claimed |
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |