Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009599 | 0.83 | KMT2A (0.58) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL6009608 | 0.83 | KMT2A (0.58) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10338896 | 0.80 | KMT2A (0.60) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL6589156 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL27855133 | 0.78 | ALDH1A1 (0.65) | ALDH1A1ABCB1 | |
| Hydrochloric Acid SCHEMBL6586295 | 0.77 | KMT2A (0.54) | KMT2AMEN1SMN1; SMN2POLBPDE4B | |
| SCHEMBL6587045 | 0.77 | DRD4 (0.57) | KMT2AMEN1PDE4B | |
| Hydrochloric Acid SCHEMBL6589249 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL3991771 | 0.76 | DRD3 (0.55) | ALDH1A1KMT2AMEN1GAAPOLB | |
| SCHEMBL6587232 | 0.76 | SIGMAR1 (0.51) | KMT2AMEN1PDE4BABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084807-A1 | Novel denzamide derivatives and process for production thereof | ASTELLAS PHARMA INC. (JP) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084807-A1 | Novel denzamide derivatives and process for production thereof | NNMT, SCN5A, QDPR | ALDH1A1 1170/4885KMT2A 483/4885MEN1 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.