Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588272 | 1.00 | KMT2A (0.50) | KMT2ANPC1MAPK1PDE4BPDE4D | |
| SCHEMBL6007696 | 1.00 | KMT2A (0.50) | KMT2ANPC1MAPK1PDE4BPDE4D | |
| Hydrochloric Acid SCHEMBL6007653 | 0.99 | KMT2A (0.49) | KMT2ANPC1MAPK1PDE4BPDE4D | |
| Hydrochloric Acid SCHEMBL6007647 | 0.99 | KMT2A (0.49) | KMT2ANPC1MAPK1PDE4BPDE4D | |
| SCHEMBL1626453 | 0.87 | MAPK1 (0.54) | KMT2ANPC1MAPK1PDE4BPDE4D | |
| Hydrochloric Acid SCHEMBL1626443 | 0.85 | MAPK1 (0.53) | KMT2ANPC1MAPK1PDE4BPDE4D | |
| SCHEMBL3721098 | 0.79 | SMN1; SMN2 (0.57) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6009649 | 0.79 | ALDH1A1 (0.53) | KMT2ANPC1MAPK1PDE4BPDE4D | |
| SCHEMBL6009646 | 0.79 | ALDH1A1 (0.53) | KMT2ANPC1MAPK1PDE4BPDE4D | |
| SCHEMBL3504812 | 0.79 | KEAP1 (0.55) | KMT2APDE4BPDE4DRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084807-A1 | Novel denzamide derivatives and process for production thereof | ASTELLAS PHARMA INC. (JP) | 2006-04-20 | — | — | US | disclosed |
| EP-1186601-B1 | NOVEL ISOQUINOLINE DERIVATIVES OR SALTS THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6573279-B1 | Drug, particularly to a novel isoquinoline derivative or its salt having an If current inhibitory effect without serious side effects such as convulsion and also to a drug, particularly a cardiac rate lowering agent, containing the | ASTELLAS PHARMA INC. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1186601-A1 | NOVEL ISOQUINOLINE DERIVATIVES OR SALTS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084807-A1 | Novel denzamide derivatives and process for production thereof | NNMT, SCN5A, QDPR | KMT2A 483/4885NPC1 3020/4885MAPK1 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.