Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009354 | 0.93 | KCNH2 (0.61) | KCNH2S1PR5KDM2BHSD11B1CCR3 | |
| SCHEMBL6009253 | 0.91 | KCNH2 (0.55) | KCNH2S1PR5DPP4DPP7SMN1; SMN2 | |
| SCHEMBL6007910 | 0.91 | KCNH2 (0.50) | KCNH2S1PR5KDM2BHSD11B1SLC6A4 | |
| SCHEMBL6810252 | 0.81 | KCNH2 (0.51) | KCNH2S1PR5KDM2BHSD11B1CCR3 | |
| SCHEMBL5790034 | 0.80 | KCNH2 (0.52) | KCNH2S1PR5KDM2BHSD11B1DPP4 | |
| SCHEMBL6007909 | 0.78 | MGLL (0.54) | KCNH2MEN1KMT2AHTR2A | |
| SCHEMBL6009245 | 0.78 | MGLL (0.54) | KCNH2MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL6007347 | 0.76 | MGLL (0.59) | KCNH2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5757243 | 0.76 | POLB (0.59) | DPP4DPP7SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6007900 | 0.76 | POLB (0.55) | DPP4DPP7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | claimed |
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |