SCHEMBL6008665

SCHEMBL6008665

CC(C)(C)c1ccc(CC(N)CCN2CCC(Cc3ccccc3)CC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 3/20 0.52
CARM1 Q86X55 2/20 0.52
PRMT3 O60678 1/20 0.52
PRMT1 Q99873 1/20 0.52
PRMT8 Q9NR22 1/20 0.52
CCR3 P51677 2/20 0.50
GRIN2D O15399 2/20 0.49
GRIN3B O60391 2/20 0.49
ADRA1D P25100 2/20 0.49
ADRA1A P35348 2/20 0.49
ADRA1B P35368 2/20 0.49
GRIN1 Q05586 2/20 0.49
GRIN2A Q12879 2/20 0.49
GRIN2B Q13224 2/20 0.49
GRIN2C Q14957 2/20 0.49
GRIN3A Q8TCU5 2/20 0.49
KCNH2 Q12809 1/20 0.48
SIGMAR1 Q99720 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6009487 0.88 GRIN2D (0.56) PRMT6CARM1PRMT3PRMT1PRMT8
Hydrochloric Acid SCHEMBL6009329 0.87 GRIN2D (0.55) PRMT6CARM1PRMT3PRMT1PRMT8
SCHEMBL6007510 0.82 CYP2J2 (0.45) ADRA1DADRA1AADRA1BKCNH2
SCHEMBL5914324 0.82 CCR3 (0.62) PRMT6CARM1PRMT3PRMT1PRMT8
SCHEMBL5914355 0.82 CCR3 (0.62) PRMT6CARM1PRMT3PRMT1PRMT8
SCHEMBL6007996 0.81 MEN1 (0.55) ADRA1DADRA1AADRA1BKCNH2
SCHEMBL20306196 0.79 SIGMAR1 (0.78) CCR3KCNH2SIGMAR1
SCHEMBL18590360 0.78 KCNH2 (0.71) CCR3GRIN2DGRIN3BADRA1DADRA1A
SCHEMBL17023759 0.78 KCNH2 (0.71) CCR3GRIN2DGRIN3BADRA1DADRA1A
SCHEMBL18609512 0.77 SLC6A2 (0.57) CCR3GRIN2DGRIN3BADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078537-B2 Phenylalkyl diamine and amide analogs SK CORPORATION (KR) 2006-07-18 US claimed
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SK BIOPHARMACEUTICALS CO., LTD. (KR) 2003-06-05 US claimed
US-7078537-B2 Phenylalkyl diamine and amide analogs SK CORPORATION (KR) 2006-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SIGMAR1, TAAR1, OPRL1 PRMT6 1600/4885CARM1 4111/4885PRMT3 1405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.