Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007996 | 0.87 | MEN1 (0.55) | CYP2J2KCNH2MEN1KMT2ANPC1 | |
| SCHEMBL6008665 | 0.82 | PRMT6 (0.52) | KCNH2ADRA1DADRA1AADRA1B | |
| SCHEMBL7238102 | 0.81 | MEN1 (0.62) | KCNH2MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL6009309 | 0.79 | SLC6A4 (0.50) | MEN1KMT2ACHRM2SLC6A2HTR2A | |
| SCHEMBL6007331 | 0.77 | CCR5 (0.52) | CCR5HTR2AS1PR5 | |
| SCHEMBL6009242 | 0.76 | MEN1 (0.57) | CYP2J2KCNH2MEN1KMT2ASLC6A2 | |
| SCHEMBL6007451 | 0.76 | MEN1 (0.57) | CYP2J2KCNH2MEN1KMT2ASLC6A2 | |
| SCHEMBL4642263 | 0.71 | EPHX1 (0.57) | KCNH2MEN1KMT2ATACR2SLC6A2 | |
| SCHEMBL6009487 | 0.70 | GRIN2D (0.56) | MEN1KMT2ASLC6A2ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL6009329 | 0.70 | GRIN2D (0.55) | MEN1KMT2ALMNASLC6A2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |