SCHEMBL6009487

SCHEMBL6009487

CC(C)(C)c1ccc(CC(N)CN2CCC(Cc3ccccc3)CC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 3/20 0.56
GRIN3B O60391 3/20 0.56
ADRA1D P25100 3/20 0.56
ADRA1A P35348 3/20 0.56
ADRA1B P35368 3/20 0.56
GRIN1 Q05586 3/20 0.56
GRIN2A Q12879 3/20 0.56
GRIN2B Q13224 3/20 0.56
GRIN2C Q14957 3/20 0.56
GRIN3A Q8TCU5 3/20 0.56
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CARM1 Q86X55 2/20 0.49
PRMT6 Q96LA8 2/20 0.49
PRMT3 O60678 1/20 0.48
PRMT1 Q99873 1/20 0.48
PRMT8 Q9NR22 1/20 0.48
CCR3 P51677 2/20 0.48
SLC6A2 P23975 2/20 0.47
SLC6A4 P31645 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6009329 0.99 GRIN2D (0.55) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL6008665 0.88 PRMT6 (0.52) GRIN2DGRIN3BADRA1DADRA1AADRA1B
Hydrochloric Acid SCHEMBL6009473 0.83 GRIN2D (0.53) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL6009351 0.80 GRIN2D (0.50) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL6009242 0.80 MEN1 (0.57) MEN1KMT2ASLC6A2SLC6A4SLC6A3
SCHEMBL6007451 0.80 MEN1 (0.57) MEN1KMT2ASLC6A2SLC6A4SLC6A3
SCHEMBL17031601 0.80 MEN1 (0.76) GRIN2DGRIN3BADRA1DADRA1AADRA1B
Hydrochloric Acid SCHEMBL6007920 0.79 GRIN2D (0.49) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL6009428 0.79 ALDH1A1 (0.53) GRIN2DGRIN3BADRA1DADRA1AADRA1B
Hydrochloric Acid SCHEMBL6007421 0.78 ALDH1A1 (0.52) GRIN2DGRIN3BADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078537-B2 Phenylalkyl diamine and amide analogs SK CORPORATION (KR) 2006-07-18 US disclosed