SCHEMBL6010068

SCHEMBL6010068

CN1CCN(CCCNC(=S)NC2CCCCC2)CC1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
MEN1 O00255 1/20 0.59
LMNA P02545 2/20 0.57
GAA P10253 2/20 0.54
QPCT Q16769 1/20 0.54
PKM P14618 1/20 0.52
EPHX1 P07099 1/20 0.51
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
SIGMAR1 Q99720 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HPGD P15428 1/20 0.45
DUSP3 P51452 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010327 0.84 GAA (0.71) KMT2AMEN1LMNAGAAQPCT
SCHEMBL16745550 0.80 PKM (0.55) KMT2AMEN1LMNAGAAQPCT
SCHEMBL19420513 0.79 KMT2A (0.76) KMT2AMEN1LMNAGAAQPCT
SCHEMBL19420702 0.79 KMT2A (0.76) KMT2AMEN1LMNAGAAQPCT
SCHEMBL10642058 0.79 KMT2A (0.65) KMT2AMEN1LMNAGAAQPCT
SCHEMBL19420646 0.78 KMT2A (0.73) KMT2AMEN1LMNAGAAQPCT
SCHEMBL13684848 0.77 KMT2A (0.96) KMT2AMEN1LMNAPKMEPHX1
SCHEMBL843571 0.75 EPHX1 (0.59) KMT2AMEN1GAAPKMEPHX1
SCHEMBL27910552 0.75 KMT2A (1.00) KMT2AMEN1LMNAPKMEPHX1
SCHEMBL23096787 0.74 KMT2A (0.68) KMT2AMEN1LMNAGAAQPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022721-B1 Method and composition for rejuvenating cells, tissues, organs, hair and nails ULRICH PETER C 2006-04-04 US disclosed
EP-1368029-A4 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS LLC (US) 2006-02-15 EP disclosed
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails ULRICH PETER C 2005-11-03 US disclosed
US-6777557-B2 Method and composition for rejuvenating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2004-08-17 US disclosed
EP-1368029-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS Farrington Pharmaceuticals, LLC (US) 2003-12-10 EP disclosed
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2002-12-12 US disclosed
WO-2002062301-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS, LLC (US) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 KMT2A 1145/4885MEN1 2886/4885LMNA 820/4885
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 KMT2A 1145/4885MEN1 2886/4885LMNA 820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.