Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324496 | 0.79 | MAPT (0.46) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL6009742 | 0.73 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL2322196 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL2346044 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL2322765 | 0.71 | SLC9A1 (0.48) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1616485 | 0.71 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL5543164 | 0.71 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL1616299 | 0.70 | KDM4E (0.58) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL27703403 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL6010443 | 0.70 | SLC9A1 (0.52) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |