SCHEMBL6010164

SCHEMBL6010164

O=C(O)[C@H](Cc1c[nH]c2ccccc12)N(OCC(O)CO)OCC(O)CO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.56
KDM4E B2RXH2 2/20 0.52
MAPT P10636 2/20 0.52
KMT2A Q03164 2/20 0.52
POLB P06746 2/20 0.52
APAF1 O14727 1/20 0.52
RECQL P46063 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
MPO P05164 1/20 0.52
TSHR P16473 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
HIF1A Q16665 1/20 0.52
DNMT1 P26358 3/20 0.46
CYP2C19 P33261 1/20 0.46
DNMT3B Q9UBC3 1/20 0.46
PKM P14618 1/20 0.46
GAA P10253 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010174 0.82 SMN1; SMN2 (0.60) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL6010161 0.82 SMN1; SMN2 (0.60) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL6010144 0.78 SMN1; SMN2 (0.67) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL828692 0.78 SMN1; SMN2 (0.67) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL828693 0.78 SMN1; SMN2 (0.67) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL6010116 0.77 SMN1; SMN2 (0.56) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL3380277 0.76 SMN1; SMN2 (0.65) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL3378235 0.76 SMN1; SMN2 (0.65) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL3380280 0.76 SMN1; SMN2 (0.65) SMN1; SMN2KDM4EMAPTKMT2APOLB
SCHEMBL1162357 0.76 SMN1; SMN2 (0.65) SMN1; SMN2KDM4EMAPTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative SEIWA KASEI COMPANY, LIMITED (JP) 2006-01-26 US disclosed
EP-1584320-A1 COSMETIC PREPARATION CONTAINING GLYCERYLAMINO ACID DERIVATIVE Seiwa Kasei Company, Limited (JP) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative GLA, GPKOW, CUTA SMN1; SMN2 3951/4885KDM4E 3805/4885MAPT 1841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.