SCHEMBL6010224

SCHEMBL6010224

CCCC(=O)C(=O)Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.71
CES1 P23141 4/20 0.71
FNTA P49354 2/20 0.64
FNTB P49356 2/20 0.64
AKR1B1 P15121 1/20 0.52
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
SLC6A2 P23975 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
POLB P06746 1/20 0.46
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CNR2 P34972 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28143905 0.85 MEN1 (0.64) CES2CES1FNTAFNTBMEN1
SCHEMBL574185 0.84 CES1 (1.00) CES2CES1FNTAFNTBAKR1B1
SCHEMBL12950241 0.83 ALDH1A1 (0.61) CES2CES1KMT2AL3MBTL1HDAC8
SCHEMBL108976 0.83 CES1 (0.77) CES2CES1FNTAFNTBAKR1B1
Hydrochloric Acid SCHEMBL3111570 0.82 CES1 (0.94) CES2CES1FNTAFNTBAKR1B1
SCHEMBL1681742 0.82 HPGD (0.50) CES2CES1FNTAFNTBMEN1
SCHEMBL6629478 0.81 CES2 (0.74) CES2CES1FNTAFNTBAKR1B1
SCHEMBL107900 0.81 L3MBTL1 (0.59) CES2CES1FNTAFNTBAKR1B1
SCHEMBL4643571 0.81 CES1 (0.74) CES2CES1FNTAFNTBAKR1B1
SCHEMBL3398677 0.80 CTBP2 (0.51) CES2CES1FNTAFNTBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4696677-A1 PHENYLHEXANEDIONE COMPOUND AND USE THEREFOR Sumitomo Chemical Company, Limited (JP) 2026-02-18 EP disclosed
WO-2024214692-A1 PHENYLHEXANEDIONE COMPOUND AND USE THEREFOR 住友化学株式会社 2024-10-17 WO disclosed
CN-107935803-B Synthetic method of 1, 2-diketone compound 浙江工业大学 2020-11-13 CN disclosed
US-20060004107-A1 Method for designing a pharmaceutical compound specific to a desired receptor, a designed compound thereby, and pharmaceutical compositions containing the same OJIMA MASANORI 2006-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004107-A1 Method for designing a pharmaceutical compound specific to a desired receptor, a designed compound thereby, and pharmaceutical compositions containing the same TBXA2R, PTAFR, PTGIR CES2 3465/4885CES1 2020/4885FNTA 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.