SCHEMBL6010259

SCHEMBL6010259

O=C(O)[C@H](Cc1ccccc1)NOCC(O)CO

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.46
NPSR1 Q6W5P4 1/20 0.44
FPR2 P25090 1/20 0.44
ALDH1A1 P00352 1/20 0.44
THRB P10828 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NAALAD2 Q9Y3Q0 2/20 0.43
MMP2 P08253 4/20 0.43
MMP9 P14780 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ADAMTS4 O75173 1/20 0.43
GPR132 Q9UNW8 1/20 0.42
FOLH1 Q04609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010139 0.89 FOLH1 (0.46) MMENAALAD2L3MBTL1FOLH1
SCHEMBL9809609 0.83 MME (0.51) MMENPSR1FPR2NAALAD2MMP2
SCHEMBL9809605 0.83 MME (0.51) MMENPSR1FPR2NAALAD2MMP2
SCHEMBL27813467 0.80 MME (0.49) MMENPSR1FPR2NAALAD2MMP2
SCHEMBL7211707 0.80 MME (0.51) MMENPSR1FPR2NAALAD2MMP2
SCHEMBL6130478 0.80 MME (0.51) MMENPSR1FPR2NAALAD2MMP2
SCHEMBL6130477 0.80 MME (0.51) MMENPSR1FPR2NAALAD2MMP2
SCHEMBL6009834 0.79 TGFBR1 (0.40) MMEALDH1A1
SCHEMBL5017006 0.78 FPR2 (0.51) MMENPSR1FPR2NAALAD2MMP2
SCHEMBL14263459 0.78 MME (0.50) MMENPSR1FPR2NAALAD2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105288634-A Preparation method of glycerin-amino acid deep eutectic solvent UNIV NANJING AGRICULTURAL 2016-02-03 CN disclosed
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative SEIWA KASEI COMPANY, LIMITED (JP) 2006-01-26 US disclosed
EP-1584320-A1 COSMETIC PREPARATION CONTAINING GLYCERYLAMINO ACID DERIVATIVE Seiwa Kasei Company, Limited (JP) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative GLA, GPKOW, CUTA MME 2180/4885NPSR1 1513/4885FPR2 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.