Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269535 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL11874663 | 0.83 | ADRA2C (0.49) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL1501851 | 0.83 | ADRA2C (0.49) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL3257654 | 0.81 | ADRA2C (0.41) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL11358599 | 0.81 | ADRA2C (0.45) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL29763626 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL173300 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL9630707 | 0.79 | ADRA2C (0.40) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL3257629 | 0.79 | ADRA2C (0.47) | GABRA1GABRB2ADRA2CADRA2AADRA2B | |
| SCHEMBL30589993 | 0.79 | ADRA2C (0.47) | GABRA1GABRB2ADRA2CADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040904-A1 | Boronate Medicaments for Preventing Thrombosis During Surgery | Trigen Holdings AG (GB) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040904-A1 | Boronate Medicaments for Preventing Thrombosis During Surgery | F9, FGB, TFPI | GABRA1 145/4885GABRB2 150/4885ADRA2C 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.