SCHEMBL9630707

SCHEMBL9630707

C=CCc1ccccc1C(c1ccccc1)c1ccccc1CC=C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 2/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
GABRA1 P14867 2/20 0.40
GABRB2 P47870 2/20 0.40
CYP2C19 P33261 1/20 0.38
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
AKR1B1 P15121 1/20 0.35
ALDH1A1 P00352 1/20 0.35
XDH P47989 1/20 0.34
ADRB2 P07550 3/20 0.33
ADRB1 P08588 3/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
LMNA P02545 1/20 0.33
HTR1A P08908 1/20 0.33
ADRB3 P13945 1/20 0.33
BDKRB2 P30411 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10348036 0.81 ADRA2C (0.45) ADRA2CADRA2AADRA2BGABRA1GABRB2
SCHEMBL8118870 0.81 XDH (0.45) ADRA2CADRA2AADRA2BGABRA1GABRB2
SCHEMBL23748247 0.81 ADRA2C (0.39) ADRA2CADRA2AADRA2BGABRA1GABRB2
SCHEMBL24353892 0.81 GABRA1 (0.42) ADRA2CADRA2AADRA2BGABRA1GABRB2
SCHEMBL11872427 0.81 SMN1; SMN2 (0.44) ADRA2CADRA2AADRA2BGABRA1GABRB2
SCHEMBL8985125 0.80 ADRA2C (0.41) ADRA2CADRA2AADRA2BGABRA1GABRB2
SCHEMBL601036 0.79 GABRA1 (0.45) ADRA2CADRA2AADRA2BGABRA1GABRB2
Hydrogen Peroxide SCHEMBL27481344 0.77 ADRA2C (0.47) ADRA2CADRA2AADRA2BGABRA1GABRB2
SCHEMBL22588790 0.76 TYR (0.41) GABRA1GABRB2CYP2C19AKR1B1ALDH1A1
Benzene SCHEMBL28085432 0.76 GABRA1 (0.54) ADRA2CADRA2AADRA2BGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0299866-B1 COMPOSITIONS OF POLYARYLALKANE OLIGOMERS, PROCESS FOR THEIR PREPARATION ATOCHEM (FR) 1992-04-15 EP disclosed
US-5071707-A Solvent is non-aromatic hydrocarbon resin ATOCHEM (FR) 1991-12-10 US disclosed
US-4956120-A REACTION OF CHLORINE WITH TOLUENE, XYLENE IN THE PRESENCE OF A FREE RADICAL CATALYST ATOCHEM (FR) 1990-09-11 US disclosed
EP-0299866-A1 Compositions of polyarylalkane oligomers, process for their preparation ELF ATOCHEM S.A. (FR) 1989-01-18 EP disclosed