Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19423175 | 0.84 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8732914 | 0.83 | PRCP (0.43) | ALDH1A1MEN1KMT2ANPSR1PRCP | |
| SCHEMBL28169156 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7460833 | 0.80 | HIF1A (0.38) | ALDH1A1NPSR1GAAL3MBTL1IDO1 | |
| SCHEMBL16191227 | 0.78 | GAA (0.39) | ALDH1A1CYP3A4LMNAGAAL3MBTL1 | |
| SCHEMBL17892465 | 0.77 | MEN1 (0.38) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28003862 | 0.77 | CA12 (0.43) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16191091 | 0.77 | KDM4E (0.44) | KMT2AGAAL3MBTL1IDO1SLC6A2 | |
| SCHEMBL4739711 | 0.76 | CA12 (0.42) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11146962 | 0.74 | ADRA2A (0.39) | GAAL3MBTL1IDO1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602562-B2 | High dielectric anisotropy and clearing point with little impact on voltage holding ratio, low temperature stability and response time | MERCK PATENT GESELLSCHAFT MIT (DE) | 2003-08-05 | — | — | US | claimed |
| US-20030113482-A1 | Realignment layer; field has a component parallel to the liquid-crystal layer; positive dielectric anisotropy | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-06-19 | — | — | US | claimed |
| EP-0408995-B1 | Liquid crystal medium with limited temperature-dependence of the d/p coefficient | MERCK PATENT GMBH (DE) | 1995-11-08 | — | — | EP | claimed |
| EP-0408995-A2 | Liquid crystal medium with limited temperature-dependence of the d/p coefficient | MERCK PATENT GmbH (DE) | 1991-01-23 | — | — | EP | claimed |
| CN-104926765-B | 4, 6-difluorodibenzofuran derivatives | 默克专利股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-11174432-B2 | 2,3-dihydrobenzothiophene derivatives | MERCK PATENT GMBH (DE) | 2021-11-16 | — | — | US | disclosed |
| CN-106045953-B | Fluorinated dibenzofuran and dibenzothiophene derivatives | 默克专利股份有限公司 | 2021-06-11 | — | — | CN | disclosed |
| EP-3645662-B1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-03-24 | — | — | EP | disclosed |
| CN-107075374-B | Substituted polyphenyl | 默克专利股份有限公司 | 2020-09-25 | — | — | CN | disclosed |
| EP-3645662-A1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | Merck Patent GmbH (DE) | 2020-05-06 | — | — | EP | disclosed |
| US-20200123444-A1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-04-23 | — | — | US | disclosed |
| WO-2019052973-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-03-21 | — | — | WO | disclosed |
| WO-1989010356-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-02 | — | — | WO | disclosed |
| WO-1989009764-A1 | CHIRAL OR ACHIRAL CYCLIC COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-10-19 | — | — | WO | disclosed |
| WO-1989008689-A1 | 2,3-DIFLUOROBENZENE DERIVATIVES AND THEIR USE AS COMPONENTS OF LIQUID CRYSTAL MEDIA | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989008637-A1 | DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989008649-A1 | HETEROCYCLIC 1,2-DIFLUOROBENZENE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| WO-1989008687-A1 | 2,3-DIFLUOROBIPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| EP-0332024-A1 | Heterocyclic derivatives of 1,2-difluorobenzene | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
| EP-0332007-A1 | Derivatives of 2,3-difluorohydroquinone | MERCK PATENT GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123444-A1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | DDT, MAGT1, MBTD1 | ALDH1A1 425/4885CYP3A4 1694/4885CYP2D6 803/4885 |
| US-11174432-B2 | 2,3-dihydrobenzothiophene derivatives | DDT, MAGT1, MBTD1 | ALDH1A1 425/4885CYP3A4 1694/4885CYP2D6 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.