Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.49 |
| ▸ | CAD | P27708 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400081 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9CADL3MBTL1 | |
| SCHEMBL6010631 | 0.89 | DPP4 (0.49) | DPP4DPP8DPP9L3MBTL1KMT2A | |
| SCHEMBL4400076 | 0.89 | DPP4 (0.49) | DPP4DPP8DPP9L3MBTL1KMT2A | |
| SCHEMBL20587887 | 0.89 | DPP4 (0.49) | DPP4DPP8DPP9L3MBTL1KMT2A | |
| SCHEMBL930492 | 0.85 | CAD (0.42) | CADL3MBTL1KMT2APOLBNOD1 | |
| SCHEMBL8644441 | 0.85 | CAD (0.42) | CADL3MBTL1KMT2APOLBNOD1 | |
| SCHEMBL15420943 | 0.80 | ALOX15 (0.53) | DPP4DPP8DPP9KMT2AALOX15 | |
| SCHEMBL5971076 | 0.80 | ALOX15 (0.53) | DPP4DPP8DPP9KMT2AALOX15 | |
| SCHEMBL210007 | 0.80 | ALOX15 (0.53) | DPP4DPP8DPP9KMT2AALOX15 | |
| SCHEMBL1217963 | 0.79 | NOD1 (0.55) | CADL3MBTL1KMT2APOLBNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701732-A2 | SULFHYDRYL PROTECTED GLUTATHIONE PRODRUG | Nagasawa, Herbert T. (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005074903-A2 | SULFHYDRYL PROTECTED GLUTATHIONE PRODRUG | NAGASAWA HERBERT T (US) | 2005-08-18 | — | — | WO | disclosed |