Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | CASP7 | P55210 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | HTR7 | P34969 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10614245 | 0.98 | HIF1A (0.69) | HIF1ALMNAADRB2TSHRCASP7 | |
| Acetic Acid SCHEMBL10614372 | 0.93 | HIF1A (0.60) | HIF1ALMNAADRB2TSHRCASP7 | |
| Hydrochloric Acid SCHEMBL11741655 | 0.86 | HIF1A (0.65) | HIF1ALMNAADRB2TSHRCASP7 | |
| Terbutaline SCHEMBL13327959 | 0.82 | LMNA (1.00) | HIF1ALMNAADRB2TSHRCASP7 | |
| Terbutaline SCHEMBL41869 | 0.82 | LMNA (1.00) | HIF1ALMNAADRB2TSHRCASP7 | |
| Terbutaline SCHEMBL4391 | 0.82 | LMNA (1.00) | HIF1ALMNAADRB2TSHRCASP7 | |
| SCHEMBL9640850 | 0.82 | ADRB2 (0.56) | HIF1ALMNAADRB2TSHRCASP7 | |
| SCHEMBL10537192 | 0.82 | ADRB2 (0.54) | HIF1ALMNAADRB2TSHRCASP7 | |
| SCHEMBL22371966 | 0.82 | ADRB2 (0.54) | HIF1ALMNAADRB2TSHRCASP7 | |
| SCHEMBL2299050 | 0.82 | ADRB2 (0.54) | HIF1ALMNAADRB2TSHRCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
| EP-1684593-A2 | METHOD OF DECREASING FAT DEPOSITS AND BODY WEIGHT IN MAMMALS AND BIRDS | Alteragon Pty Ltd (AU) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005051092-A2 | METHOD OF DECREASING FAT DEPOSITS AND BODY WEIGHT IN MAMMALS AND BIRDS | ALTERAGON PTY LTD (AU) | 2005-06-09 | — | — | WO | disclosed |
| US-4754047-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0110202-B1 | PROCESS FOR THE PREPARATION OF PHENYLETHANOL AMINES | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1986-10-15 | — | — | EP | disclosed |
| US-4522822-A | Phenylethane derivatives and acid addition salts thereof for increasing lean meat deposition and/or improving lean meat to fat ratio in warm blooded animals | AMERICAN CYANAMID COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4501751-A | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby | AMERICAN CYANAMID COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0110202-A2 | Process for the preparation of phenylethanol amines | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1984-06-13 | — | — | EP | disclosed |
| EP-0026298-B1 | METHOD FOR PROMOTING GROWTH AND REDUCING FAT IN ANIMALS USING PHENYLETHANOLAMINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1984-04-18 | — | — | EP | disclosed |
| US-4407819-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| US-4404222-A | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby | AMERICAN CYANAMID COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0026298-A1 | Method for promoting growth and reducing fat in animals using phenylethanolamine derivatives | AMERICAN CYANAMID COMPANY (US) | 1981-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | NR5A1, ESRRA, AR | HIF1A 1391/4885LMNA 2695/4885ADRB2 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.