Terbutaline

Terbutaline

SCHEMBL4391

CC(C)(C)NCC(O)c1cc(O)cc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB2

The experimentally established mechanism targets of Terbutaline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 5/20 1.00
LMNA P02545 5/20 1.00
HIF1A Q16665 4/20 1.00
TSHR P16473 4/20 1.00
KMT2A Q03164 3/20 1.00
CASP7 P55210 2/20 1.00
CYP3A4 P08684 2/20 1.00
CYP2C9 P11712 1/20 1.00
KDM4E B2RXH2 2/20 0.84
MEN1 O00255 2/20 0.84
BLM P54132 2/20 0.84
CASP1 P29466 1/20 0.84
SMN1; SMN2 Q16637 1/20 0.84
ADRA1A P35348 2/20 0.60
ADRB1 P08588 2/20 0.60
HTR1A P08908 1/20 0.60
SLC6A2 P23975 1/20 0.60
SLC6A4 P31645 1/20 0.60
OPRK1 P41145 1/20 0.60
SLC6A3 Q01959 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terbutaline SCHEMBL41869 1.00 LMNA (1.00) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL13327959 1.00 LMNA (1.00) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL404480 0.98 ADRB2 (0.96) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL11703058 0.98 ADRB2 (0.96) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL41870 0.92 LMNA (1.00) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL9614480 0.92 LMNA (1.00) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL28324621 0.92 LMNA (0.84) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL26462 0.92 LMNA (1.00) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL5178614 0.92 LMNA (1.00) LMNAADRB2HIF1ATSHRKMT2A
Terbutaline SCHEMBL3937997 0.92 LMNA (1.00) LMNAADRB2HIF1ATSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 41310 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423298-B1 None US claimed
CN-122094963-A Cardioprotective lipids and methods of use 2026-05-26 CN claimed
WO-2026106917-A1 EDIBLE TRANSMUCOSAL DRUG DELIVERY METHOD USING AN INTERMEDIATE CAPSULE AS A TEMPORARY VESSEL BioPhysics Pharma, Inc. (US) 2026-05-21 WO claimed
US-20260132115-A1 SUBSTITUTED 3-FLUOROBENZENEPROPANOATE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF TIANJIN GUDUI BIO PHARM CO LTD (CN) 2026-05-14 US claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
US-12617809-B2 Cardioprotective lipid and method of use SIGNPATH PHARMA, INC. (US) 2026-05-05 US claimed
EP-4731082-A1 METHOD AND SYSTEM FOR FETAL MONITORING AND TREATMENT FMSA Inc (US) 2026-04-29 EP claimed
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
EP-0036426-A1 NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES. INTERX RESEARCH CORP (US) 1981-09-30 EP claimed
US-4292302-A Polymeric diffusion matrix containing terbutaline KEY PHARMACEUTICALS, INC. (US) 1981-09-29 US claimed
US-4288538-A SIMULTANEOUS ENZYME CONVERSION AND IMMUNOASSAY OF STEROID CONJUGATES BAXTER TRAVENOL LABORATORIES, INC. (US) 1981-09-08 US claimed
US-4275219-A Novel process and intermediates useful in the preparation of sympathomimetic amines INTERX RESEARCH CORPORATION (US) 1981-06-23 US claimed
WO-1981000849-A1 NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES INTERX RESEARCH CORP (US) 1981-04-02 WO claimed
US-4256108-A Microporous-semipermeable laminated osmotic system ALZA CORPORATION (US) 1981-03-17 US claimed
US-4199578-A TREATMENT OF ASTHMA OR HAY FEVER FISONS LIMITED (GB) 1980-04-22 US claimed
US-4153677-A MICROENCAPSULATED BRONCHODILATOR AGENT, ETHYL CELLULOSE FILM STERLING DRUG INC. (US) 1979-05-08 US claimed
US-4147767-A CROSSLINKED WITH FORMALDEHYDE OR GLUTARALDEHYDE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-04-03 US claimed
US-3937838-A BRONCHODILATORS, DIHYDROXYPHENYL ETHANOLAMINES AKTIEBOLAGET DRACO (SW) 1976-02-10 US claimed