Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69553 | 0.77 | BACE1 (0.60) | BACE1TSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL69552 | 0.77 | BACE1 (0.60) | BACE1TSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL30294965 | 0.77 | MGLL (0.45) | BACE1STSTSHRLMNAKDM4E | |
| SCHEMBL14261772 | 0.76 | EED (0.48) | STSKDM4EALDH1A1 | |
| SCHEMBL6982058 | 0.75 | ALDH1A1 (0.43) | BACE1STSTSHRLMNAKDM4E | |
| SCHEMBL6982060 | 0.75 | ALDH1A1 (0.43) | BACE1STSTSHRLMNAKDM4E | |
| SCHEMBL6982055 | 0.75 | ALDH1A1 (0.43) | BACE1STSTSHRLMNAKDM4E | |
| SCHEMBL6974542 | 0.74 | STS (0.42) | BACE1STSTSHRLMNAKDM4E | |
| SCHEMBL6980909 | 0.74 | STS (0.42) | BACE1STSTSHRLMNAKDM4E | |
| SCHEMBL10069268 | 0.74 | P4HB (0.53) | LMNAKDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785415-B1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |