Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | WEE1 | P30291 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839714 | 0.91 | MAPT (0.59) | MAPTGAAHTTTSHRMAPK1 | |
| SCHEMBL347390 | 0.91 | MAPT (0.59) | MAPTGAAHTTTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL10604756 | 0.89 | MAPT (0.57) | MAPTGAAHTTTSHRMAPK1 | |
| SCHEMBL6011401 | 0.89 | ALDH1A1 (0.53) | MAPTGAAHTTTSHRMAPK1 | |
| SCHEMBL6011394 | 0.89 | ALDH1A1 (0.56) | MAPTGAAHTTMAPK1IMPDH2 | |
| SCHEMBL6011404 | 0.87 | MAOB (0.53) | MAPTGAAHTTTSHRMAPK1 | |
| SCHEMBL6011416 | 0.86 | ALDH1A1 (0.50) | MAPTGAAHTTTSHRMAPK1 | |
| SCHEMBL3787198 | 0.86 | ALDH1A1 (0.50) | MAPTGAAHTTTSHRMAPK1 | |
| SCHEMBL6011487 | 0.86 | ALDH1A1 (0.47) | MAPTGAAHTTTSHRMAPK1 | |
| SCHEMBL30839803 | 0.83 | MAPT (0.52) | MAPTGAAHTTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082169-B | Preparation method of polyurethane chain extender 2-methoxy-2' -aminobenzidine | 江苏康恒化工有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-116082169-A | Preparation method of polyurethane chain extender 2-methoxy-2' -aminobenzidine | 江苏康恒化工有限公司 | 2023-05-09 | — | — | CN | claimed |
| EP-1355619-B1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AG (DE) | 2006-12-06 | — | — | EP | claimed |
| CN-116082169-B | Preparation method of polyurethane chain extender 2-methoxy-2' -aminobenzidine | 江苏康恒化工有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-116082169-A | Preparation method of polyurethane chain extender 2-methoxy-2' -aminobenzidine | 江苏康恒化工有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116082169-A | Preparation method of polyurethane chain extender 2-methoxy-2' -aminobenzidine | 江苏康恒化工有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116082169-A | Preparation method of polyurethane chain extender 2-methoxy-2' -aminobenzidine | 江苏康恒化工有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-1355619-B1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AG (DE) | 2006-12-06 | — | — | EP | disclosed |
| US-7056347-B2 | Coloring agents for keratin fibers containing (1,1′-biphenyl)-2,4-diamine derivatives in addition to novel (1,1′-biphenyl)-2,4-diamine-derivatives | WELLA AG (DE) | 2006-06-06 | — | — | US | disclosed |
| EP-1355619-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-20030172470-A1 | Colouring agents for keratin fibres containing (1.1'-biphenyl)-2.4-diamine derivatives in addition to novel (1.1'-biphenyl)-2.4-diamine-derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-09-18 | — | — | US | disclosed |
| WO-2002062307-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172470-A1 | Colouring agents for keratin fibres containing (1.1'-biphenyl)-2.4-diamine derivatives in addition to novel (1.1'-biphenyl)-2.4-diamine-derivatives | KRT18, DSP, DSG1 | MAPT 463/4885GAA 4442/4885HTT 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.