Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.60 |
| ▸ | CA1 | P00915 | 6/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182658 | 0.88 | LMNA (0.76) | CA2CA1PTGS2PTGS1KDM4E | |
| SCHEMBL13741969 | 0.87 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL27814041 | 0.87 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL6535038 | 0.87 | LMNA (0.56) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL10931933 | 0.86 | CA2 (0.60) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL453442 | 0.86 | CA2 (0.60) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL4196236 | 0.86 | LMNA (0.78) | CA2CA1LMNACA9NLRP3 | |
| SCHEMBL11461045 | 0.84 | CA2 (0.58) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL8338055 | 0.82 | GAA (0.57) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL5069150 | 0.82 | LMNA (0.54) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113474388-B | Method for converting phenyl isocyanate | 陶氏环球技术有限责任公司 | 2024-03-22 | — | — | CN | disclosed |
| US-7026477-B1 | Process for preparing substituted phenylsulfonylureas from sulfonyl halides | AVENTIS CROPSCIENCE GMBH (DE) | 2006-04-11 | — | — | US | disclosed |