SCHEMBL453442

SCHEMBL453442

O=C(O)NS(=O)(=O)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.60
MMP2 P08253 2/20 0.60
CA1 P00915 1/20 0.60
MMP1 P03956 1/20 0.60
MMP9 P14780 1/20 0.60
MMP8 P22894 1/20 0.60
MMP13 P45452 1/20 0.60
PTGS2 P35354 3/20 0.58
PTGS1 P23219 2/20 0.58
KDM4E B2RXH2 2/20 0.58
HPGD P15428 1/20 0.56
BCAT1 P54687 1/20 0.53
LMNA P02545 2/20 0.53
IL1RN P18510 1/20 0.52
KEAP1 Q14145 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
CA12 O43570 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
KAT6A Q92794 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6012074 0.86 CA2 (0.60) CA2MMP2CA1MMP1MMP9
SCHEMBL10931933 0.86 CA2 (0.60) CA2MMP2CA1MMP1MMP9
SCHEMBL11461045 0.84 CA2 (0.58) CA2MMP2CA1MMP1MMP9
Biphenyl SCHEMBL9176116 0.82 LMNA (0.64) CA2MMP2CA1MMP1MMP9
SCHEMBL370189 0.82 CA2 (0.56) CA2MMP2CA1MMP1MMP9
SCHEMBL209631 0.82 CA2 (0.56) CA2MMP2CA1MMP1MMP9
SCHEMBL209632 0.82 DHFR (0.66) CA2MMP2CA1MMP1MMP9
SCHEMBL2172235 0.82 CA2 (0.61) CA2MMP2CA1MMP1MMP9
SCHEMBL10817093 0.82 CA2 (0.56) CA2MMP2CA1MMP1MMP9
SCHEMBL27583034 0.82 CA2 (0.56) CA2MMP2CA1MMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117919275-A Dendrimer-tannic acid/iron composite nano platform loaded with copper peroxide and preparation and application thereof 东华大学 2024-04-26 CN claimed
CN-110499091-A A kind of chitin modified polyphenyl sulfonamide antimicrobial coating of nano silver-and its preparation method WANG HUAN 2019-11-26 CN claimed
JP-3920323-B2 2007-05-30 JP claimed
WO-2006047045-A2 STABILIZED CHLORINE BLEACH IN ALKALINE DETERGENT COMPOSITION AND METHOD OF MAKING AND USING THE SAME DELAVAL HOLDING AB (SE) 2006-05-04 WO claimed
EP-0874809-B1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2003-08-27 EP claimed
US-6239175-B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2001-05-29 US claimed
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP claimed
EP-0723534-B1 PHENYLSULFONYL UREAS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-07-29 EP claimed
EP-0404440-B1 Substituted sulfonamides and related compounds in the treatment of asthma, arthritis, and related diseases PFIZER (US) 1997-11-05 EP claimed
JP-2544566-B2 1996-10-16 JP claimed
EP-0085028-A2 N-Phenylsulfonyl-N'-pyrimidinyl and triazinyl ureas CIBA-GEIGY AG (CH) 1983-08-03 EP claimed
EP-0082108-A1 N-phenylsulfonyl-N'-pyrimidinyl and triazinyl urea CIBA-GEIGY AG (CH) 1983-06-22 EP claimed
EP-0072347-A1 N-phenylsulfonyl-N'-pyrimidinyl and -triazinyl ureas CIBA-GEIGY AG (CH) 1983-02-16 EP claimed
EP-0070802-A2 N-phenylsulfonyl-N'-pyrimidinyl and ditto triazinyl ureas CIBA-GEIGY AG (CH) 1983-01-26 EP claimed
US-4334911-A THIOCARBAMATE AND TRIAZINE MIXTURE WITH N-BENZENE-SULFONYL STAUFFER CHEMICAL COMPANY (US) 1982-06-15 US claimed
EP-0044809-A1 N-(2-substituted phenylsulfonyl)-N'-triazinyl ureas CIBA-GEIGY AG (CH) 1982-01-27 EP claimed
EP-0044808-A2 N-phenylsulfonyl-N'-pyrimidinyl- and -triazinyl ureas CIBA-GEIGY AG (CH) 1982-01-27 EP claimed
EP-0044807-A2 N-phenylsulfonyl-N'-pyrimidinyl- and -triazinyl ureas CIBA-GEIGY AG (CH) 1982-01-27 EP claimed
US-4168152-A TRIAZINE HERBICIDES WITH N-BENZENESULFONYL CARBAMATES AS HERBICIDE ANTIBOTES STAUFFER CHEMICAL COMPANY (US) 1979-09-18 US claimed
US-3933894-A HERBICIDES MONSANTO COMPANY (US) 1976-01-20 US claimed