Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.43 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | METAP2 | P50579 | 4/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6012205 | 0.75 | PREP (0.38) | PREP | |
| SCHEMBL833488 | 0.74 | TDP1 (0.45) | CXCR2RXRAMETAP2RXRBRXRG | |
| SCHEMBL7598320 | 0.72 | MAPK1 (0.49) | KDM4EMAPTFABP4 | |
| SCHEMBL7026132 | 0.71 | WDR5 (0.50) | CXCR2KDM4E | |
| SCHEMBL3932327 | 0.71 | CXCR2 (0.47) | CXCR2RXRAMETAP2RXRBRXRG | |
| SCHEMBL19526323 | 0.70 | ACACB (0.33) | — | |
| SCHEMBL564223 | 0.69 | METAP2 (0.47) | CXCR2RXRAMETAP2RXRBRXRG | |
| SCHEMBL3551316 | 0.69 | MEN1 (0.41) | RXRAMETAP2RXRBRXRGKDM4E | |
| SCHEMBL6419613 | 0.69 | RXRA (0.46) | CXCR2RXRAMETAP2RXRBRXRG | |
| SCHEMBL21973640 | 0.69 | KMT2A (0.44) | KDM4EMAPTPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012322-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |