Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20023762 | 0.83 | L3MBTL1 (0.39) | HCAR3L3MBTL1ACHEKDM4EALDH1A1 | |
| SCHEMBL2373382 | 0.81 | L3MBTL1 (0.41) | HCAR3L3MBTL1ACHEKMOKDM4E | |
| SCHEMBL5393771 | 0.75 | L3MBTL1 (0.34) | L3MBTL1ACHEKDM4EALDH1A1LMNA | |
| SCHEMBL20874549 | 0.71 | ALDH1A1 (0.41) | HCAR3L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL26988158 | 0.70 | KMO (0.33) | KMOKDM4E | |
| SCHEMBL27137504 | 0.70 | KMO (0.33) | KMOKDM4E | |
| SCHEMBL7449090 | 0.70 | KMT2A (0.36) | L3MBTL1KDM4EKDM4CALDH1A1LMNA | |
| SCHEMBL15651629 | 0.69 | ADORA2A (0.36) | ACHEKDM4EALDH1A1 | |
| SCHEMBL14445241 | 0.69 | KMO (0.49) | L3MBTL1KMOKDM4EALDH1A1MAPT | |
| SCHEMBL22143750 | 0.67 | L3MBTL1 (0.54) | HCAR3L3MBTL1ACHEKDM4EKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270849-A1 | Process for producing pyrimidin-4-one compound | UBE INDUSTRIES, LTD. (JP) | 2006-11-30 | — | — | US | disclosed |
| EP-1637523-A1 | PROCESS FOR PRODUCING PYRIMIDIN-4-ONE COMPOUND | Ube Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270849-A1 | Process for producing pyrimidin-4-one compound | DDC, ODC1, APRT | HCAR3 2932/4885L3MBTL1 4697/4885ACHE 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.