Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014267 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014314 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014296 | 0.85 | KMT2A (0.41) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014269 | 0.84 | KMT2A (0.40) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014233 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014317 | 0.84 | GABRA1 (0.41) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014311 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014274 | 0.83 | KMT2A (0.39) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014246 | 0.82 | KMT2A (0.39) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014257 | 0.82 | KMT2A (0.39) | ALDH1A1KMT2AKDM4EMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | disclosed |