Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014311 | 0.96 | ALDH1A1 (0.39) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6014246 | 0.95 | KMT2A (0.39) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6014278 | 0.95 | KMT2A (0.39) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6014259 | 0.84 | ALDH1A1 (0.43) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6014230 | 0.84 | NPC1 (0.39) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6014267 | 0.84 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6014314 | 0.83 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1KDM4EHTT | |
| Urea SCHEMBL6014279 | 0.82 | L3MBTL1 (0.42) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6014296 | 0.82 | KMT2A (0.41) | KMT2AALDH1A1MEN1KDM4EHTT | |
| SCHEMBL6014317 | 0.80 | GABRA1 (0.41) | KMT2AALDH1A1MEN1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | disclosed |