Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014259 | 0.85 | ALDH1A1 (0.43) | KMT2AL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL6014267 | 0.84 | ALDH1A1 (0.44) | KMT2AL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL6014314 | 0.83 | ALDH1A1 (0.41) | KMT2AL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL6014269 | 0.82 | KMT2A (0.40) | KMT2AL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL6014317 | 0.81 | GABRA1 (0.41) | KMT2AL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL6014233 | 0.81 | ALDH1A1 (0.41) | KMT2AL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6014274 | 0.80 | KMT2A (0.39) | KMT2AL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL6014311 | 0.80 | ALDH1A1 (0.39) | KMT2AL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL6014278 | 0.79 | KMT2A (0.39) | KMT2AL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL6014246 | 0.79 | KMT2A (0.39) | KMT2AL3MBTL1ATMALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | disclosed |