Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548338 | 0.96 | ALDH1A1 (0.42) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL6014274 | 0.92 | KMT2A (0.39) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL6014257 | 0.91 | KMT2A (0.39) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL6014317 | 0.88 | GABRA1 (0.41) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL6014314 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014267 | 0.78 | ALDH1A1 (0.44) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL6014249 | 0.73 | MAPT (0.42) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014259 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL30682087 | 0.70 | KMT2A (0.46) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL6014296 | 0.70 | KMT2A (0.41) | ALDH1A1KMT2AKDM4EMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | disclosed |