Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895787 | 0.85 | EPHX1 (0.73) | EPHX1ANPEPSLC6A4SIGMAR1SLC6A2 | |
| SCHEMBL895668 | 0.85 | EPHX1 (0.73) | EPHX1ANPEPSLC6A4SIGMAR1SLC6A2 | |
| SCHEMBL43428 | 0.85 | EPHX1 (0.73) | EPHX1ANPEPSLC6A4SIGMAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL8842804 | 0.83 | EPHX1 (0.70) | EPHX1ANPEPSLC6A4SIGMAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL8734599 | 0.83 | EPHX1 (0.70) | EPHX1ANPEPSLC6A4SIGMAR1SLC6A2 | |
| SCHEMBL2146 | 0.81 | MEN1 (0.64) | SIGMAR1MAOAMEN1KMT2ATDP1 | |
| Benzene SCHEMBL7471176 | 0.81 | MEN1 (0.64) | SIGMAR1MAOAMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL1551607 | 0.79 | MEN1 (0.61) | SIGMAR1MAOAMEN1KMT2ATDP1 | |
| SCHEMBL21065761 | 0.79 | MEN1 (0.61) | SIGMAR1MAOAMEN1KMT2ATDP1 | |
| SCHEMBL10813092 | 0.79 | MEN1 (0.61) | SIGMAR1MAOAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078406-B2 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | Life Technologies Corporation | 2004-12-09 | — | — | US | disclosed |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | DHFR, FPR1, CYP1A1 | EPHX1 912/4885ANPEP 2443/4885SLC6A4 3578/4885 |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | DHFR, FPR1, CYP1A1 | EPHX1 912/4885ANPEP 2443/4885SLC6A4 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.