Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.73 |
| ▸ | ANPEP | P15144 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895668 | 1.00 | EPHX1 (0.73) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| SCHEMBL43428 | 1.00 | EPHX1 (0.73) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL8734599 | 0.98 | EPHX1 (0.70) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL8842804 | 0.98 | EPHX1 (0.70) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| SCHEMBL17906518 | 0.87 | SLC6A4 (0.56) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| SCHEMBL16945131 | 0.87 | SLC6A4 (0.56) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| SCHEMBL8749872 | 0.87 | EPHX1 (0.55) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| SCHEMBL6014598 | 0.85 | EPHX1 (0.53) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| SCHEMBL28656 | 0.85 | EPHX1 (1.00) | EPHX1ANPEPSLC6A4SLC6A2TAAR1 | |
| SCHEMBL13696737 | 0.82 | LTA4H (0.72) | SLC6A2MAOASLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2026-01-29 | — | — | US | claimed |
| US-20240150732-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2024-05-09 | — | — | US | claimed |
| US-11939602-B2 | Transaminase polypeptides | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2024-03-26 | — | — | US | claimed |
| WO-2023214011-A1 | ENZYMATIC METHOD FOR PREPARING (R)-3-AMINO-4-ARYL-BUTANOIC ACID DERIVATIVES | ENZYMICALS AG (DE) | 2023-11-09 | — | — | WO | claimed |
| EP-4273254-A1 | ENZYMATIC METHOD FOR PREPARING (R)-3-AMINO-4-ARYL-BUTANOIC ACID DERIVATIVES | Enzymicals AG (DE) | 2023-11-08 | — | — | EP | claimed |
| US-20230120624-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2023-04-20 | — | — | US | claimed |
| US-11542485-B2 | Transaminase polypeptides | CODEXIS, INC. (US) | 2023-01-03 | — | — | US | claimed |
| US-20210230564-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-07-29 | — | — | US | claimed |
| US-10995323-B2 | Transaminase polypeptides | CODEXIS, INC. (US) | 2021-05-04 | — | — | US | claimed |
| EP-3354727-B1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2020-10-07 | — | — | EP | claimed |
| US-20180201911-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-07-19 | — | — | US | claimed |
| US-9944909-B2 | Polynucleotides encoding transaminase polypeptides | CODEXIS, INC. (US) | 2018-04-17 | — | — | US | claimed |
| EP-2385983-B1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2017-12-20 | — | — | EP | claimed |
| US-20170073651-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-03-16 | — | — | US | claimed |
| US-9512410-B2 | Engineered transaminase polypeptides | CODEXIS, INC. (US) | 2016-12-06 | — | — | US | claimed |
| US-20150210988-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-07-30 | — | — | US | claimed |
| EP-2385983-A2 | TRANSAMINASE POLYPEPTIDES | Codexis, Inc. (US) | 2011-11-16 | — | — | EP | claimed |
| US-D646886-S1 | Tip of an umbrella | Pro Performance Sports, L.L.C. (US) | 2011-10-18 | — | — | US | claimed |
| US-20100209981-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS, INC. (US) | 2010-08-19 | — | — | US | claimed |
| WO-2010081053-A2 | TRANSAMINASE POLYPEPTIDES | CODEXIS, INC. (US) | 2010-07-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | GOT1, OAT, PEPD | EPHX1 3023/4885ANPEP 75/4885SLC6A4 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.