Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 2/20 | 0.58 |
| ▸ | TK1 | P04183 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | TK2 | O00142 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658758 | 1.00 | CDA (0.58) | CDATK1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL15893325 | 1.00 | CDA (0.58) | CDATK1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL21423103 | 1.00 | CDA (0.58) | CDATK1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL658757 | 1.00 | CDA (0.58) | CDATK1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL4318242 | 1.00 | CDA (0.58) | CDATK1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL15895803 | 1.00 | CDA (0.58) | CDATK1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL31685506 | 0.81 | TYMS (0.48) | — | |
| SCHEMBL22916929 | 0.79 | CDA (0.44) | CDATK1TSHR | |
| SCHEMBL23240762 | 0.78 | CDA (0.58) | CDATK1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL172249 | 0.78 | CDA (0.58) | CDATK1LMNASMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063926-A1 | L-nucleic acid derivative and processes for the synthesis thereof | MITSUI CHEMICALS, INC. (JP) | 2004-04-01 | — | — | US | claimed |
| EP-1348712-A1 | L-NUCLEIC ACID DERIVATIVES AND PROCESSES FOR THE SYNTHESIS THEREOF | Mitsui Chemicals, Inc. (JP) | 2003-10-01 | — | — | EP | claimed |
| US-20210196723-A1 | Modulators of DUX4 for Regulation of Muscle Function | SONIC MASTER LTD (VG) | 2021-07-01 | — | — | US | disclosed |
| US-9283242-B2 | Uses of dihydro bases | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-15 | — | — | US | disclosed |
| US-20140206639-A1 | USES OF DIHYDRO BASES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-07-24 | — | — | US | disclosed |
| US-7125983-B2 | L-nucleic acid derivatives and process for the synthesis thereof | MITSUI CHEMICALS, INC. (JP) | 2006-10-24 | — | — | US | disclosed |
| US-20040063926-A1 | L-nucleic acid derivative and processes for the synthesis thereof | MITSUI CHEMICALS, INC. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1348712-A1 | L-NUCLEIC ACID DERIVATIVES AND PROCESSES FOR THE SYNTHESIS THEREOF | Mitsui Chemicals, Inc. (JP) | 2003-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206639-A1 | USES OF DIHYDRO BASES | DPYD, DHODH, HPRT1 | CDA 120/4885TK1 166/4885LMNA 701/4885 |
| US-20210196723-A1 | Modulators of DUX4 for Regulation of Muscle Function | DDX21, MBNL1, MECP2 | CDA 813/4885TK1 2815/4885LMNA 1943/4885 |
| US-20040063926-A1 | L-nucleic acid derivative and processes for the synthesis thereof | TYMS, RNGTT, DTYMK | CDA 72/4885TK1 23/4885LMNA 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.