SCHEMBL658758

SCHEMBL658758

O=C1CCN([C@@H]2CC(O)[C@H](CO)O2)C(=O)N1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CDA P32320 2/20 0.58
TK1 P04183 3/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ALOX12 P18054 1/20 0.43
ADRA1A P35348 1/20 0.43
ADRB1 P08588 1/20 0.42
DNMT1 P26358 1/20 0.42
TK2 O00142 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015192 1.00 CDA (0.58) CDATK1LMNASMN1; SMN2ALOX12
SCHEMBL15893325 1.00 CDA (0.58) CDATK1LMNASMN1; SMN2ALOX12
SCHEMBL21423103 1.00 CDA (0.58) CDATK1LMNASMN1; SMN2ALOX12
SCHEMBL658757 1.00 CDA (0.58) CDATK1LMNASMN1; SMN2ALOX12
SCHEMBL4318242 1.00 CDA (0.58) CDATK1LMNASMN1; SMN2ALOX12
SCHEMBL15895803 1.00 CDA (0.58) CDATK1LMNASMN1; SMN2ALOX12
SCHEMBL31685506 0.81 TYMS (0.48)
SCHEMBL22916929 0.79 CDA (0.44) CDATK1TSHR
SCHEMBL23240762 0.78 CDA (0.58) CDATK1LMNASMN1; SMN2ALOX12
SCHEMBL172249 0.78 CDA (0.58) CDATK1LMNASMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158770-B2 Content dependent inhibitors of cytidine deaminases and uses thereof UNIVERSITY OF ROCHESTER (US) 2012-04-17 US claimed
US-20090099105-A1 Content dependent inhibitors of cytidine deaminases and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-04-16 US claimed
WO-2005115410-A2 CONTEXT DEPENDENT INHIBITORS OF CYTIDINE DEAMINASES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2005-12-08 WO claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
US-20240117337-A1 METHODS AND POLYNUCLEOTIDES FOR AMPLIFYING A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-04-11 US disclosed
US-20240076719-A9 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-03-07 US disclosed
US-20230295694-A1 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-09-21 US disclosed
US-11725205-B2 Methods and polynucleotides for amplifying a target polynucleotide OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-15 US disclosed
US-20100317004-A1 PROBES Life Technologies Corporation (US) 2010-12-16 US disclosed
EP-2242761-A1 METHOD OF MYCOTOXIN DETECTION Neoventures Biotechnology Inc. (CA) 2010-10-27 EP disclosed
WO-2009086621-A1 METHOD OF MYCOTOXIN DETECTION NEOVENTURES BIOTECHNOLOGY INC. (CA) 2009-07-16 WO disclosed
US-20090099105-A1 Content dependent inhibitors of cytidine deaminases and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-04-16 US disclosed
EP-1585835-B1 Nucleic acid probes and method for detecting a target nucleic acid sequence comprising two or more cis-located nucleic acid regions DYNAL BIOTECH LTD (GB) 2007-04-18 EP disclosed
US-20060269916-A1 Probes DYNAL BIOTECH INC. 2006-11-30 US disclosed
WO-2005115410-A2 CONTEXT DEPENDENT INHIBITORS OF CYTIDINE DEAMINASES AND USES THEREOF UNIVERSITY OF ROCHESTER (US) 2005-12-08 WO disclosed
EP-1585835-A2 NUCLEIC ACID PROBES AND METHOD FOR DETECTING A TARGET NUCLEIC ACID SEQUENCE COMPRISE TWO OR MORE CIS- LOCATED NUCLEIC ACID REGIONS Dynal Biotech Limited (GB) 2005-10-19 EP disclosed
WO-2004048611-A2 NUCLEIC ACID PROBES AND METHOD FOR DETECTING A TARGET NUCLEIC ACID SEQUENCE COMPRISE TWO OR MORE CIS- LOCATED NUCLEIC ACID REGIONS DYNAL BIOTECH LIMITED (GB) 2004-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM CDA 366/4885TK1 472/4885LMNA 171/4885
US-20090099105-A1 Content dependent inhibitors of cytidine deaminases and uses thereof DCTD, CDA, ADA CDA 2/4885TK1 178/4885LMNA 2870/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 CDA 293/4885TK1 1713/4885LMNA 3119/4885
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 CDA 275/4885TK1 950/4885LMNA 240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.