Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6015240

CCN(CC)c1ccc([N+]#N)cc1C.[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 1/20 0.33
S100B P04271 1/20 0.33
RARA P10276 1/20 0.31
RARB P10826 1/20 0.31
RARG P13631 1/20 0.31
ALDH3A1 P30838 1/20 0.30
CRHR1 P34998 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10493713 0.98 S100B (0.34) ALDH1A3S100BRARARARBRARG
SCHEMBL11060519 0.96 ALDH1A3 (0.33) ALDH1A3S100BRARARARBRARG
Zinc Ion SCHEMBL11060524 0.96 ALDH1A3 (0.33) ALDH1A3S100BRARARARBRARG
Trifluoromethanesulfonic Acid SCHEMBL11063363 0.83 KCNH2 (0.33) CRHR1
Hydrochloric Acid SCHEMBL11873702 0.81 ALDH1A3 (0.37) ALDH1A3ALDH3A1
SCHEMBL10786222 0.79 ALDH1A3 (0.38) ALDH1A3ALDH3A1
SCHEMBL10493605 0.77 ESR1 (0.37)
SCHEMBL10809050 0.76 ALDH1A3 (0.36) ALDH1A3ALDH3A1
SCHEMBL4600856 0.76 ALDH1A1 (0.40) CRHR1
SCHEMBL12297193 0.75 HTT (0.33) ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558446-B1 THERMAL GENERATION OF A MASK FOR FLEXOGRAPHY KODAK POLYCHROME GRAPHICS LLC (US) 2006-08-16 EP disclosed
US-6960419-B2 Antihalation dye for negative-working printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2005-11-01 US disclosed
EP-1558446-A1 THERMAL GENERATION OF A MASK FOR FLEXOGRAPHY Kodak Polychrome Graphics, LLC (US) 2005-08-03 EP disclosed
US-20050130064-A1 ANTIHALATION DYE FOR NEGATIVE-WORKING PRINTING PLATES CITICORP NORTH AMERICA, INC., AS AGENT 2005-06-16 US disclosed
US-6794107-B2 THERMALLY IMAGEABLE VESICULAR IMAGING COMPOSITION COMPRISING SENSITIZER, POLYMER, AND PHOTOTHERMAL CONVERSION MATERIAL; EXPOSURE TO ULTRAVIOLET AND/OR VISIBLE RADIATION; DEVELOPMENT TO PRODUCE PRINTING PLATE KODAK POLYCHROME GRAPHICS LLC 2004-09-21 US disclosed
WO-2004039601-A1 THERMAL GENERATION OF A MASK FOR FLEXOGRAPHY KODAK POLYCHROME GRAPHICS LLC (US) 2004-05-13 WO disclosed
US-20040081908-A1 Thermal generation of a mask for flexography EASTMAN KODAK COMPANY 2004-04-29 US disclosed
EP-0109286-A2 Image stabilizers for vesicular film MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-05-23 EP disclosed
US-4430414-A BENZOIC ACID DERIVATIVES AS STABILIZERS FOR HOMO-(OR CO-)POLYMERS OF CHLOROACRYLONITRILE AND LIGHT SENSITIVE AGENT MINNESOTA MINING & MANUFACTURING COMPANY (US) 1984-02-07 US disclosed
US-4283477-A POLYSULFONAMIDE SEPARATION POLYMER FOR STORAGE STABILITY EASTMAN KODAK COMPANY (US) 1981-08-11 US disclosed
US-4199359-A Photographic screen stencil printing process XEROX CORPORATION (US) 1980-04-22 US disclosed
US-4103072-A Method of producing diazotype photoprinting material WEBER-VALENTINE COMPANY, INC. (US) 1978-07-25 US disclosed