Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015749 | 0.95 | KMT2A (0.51) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL6015923 | 0.89 | KMT2A (0.62) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL6016069 | 0.88 | KMT2A (0.64) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL6015996 | 0.85 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL6015685 | 0.77 | HTR6 (0.63) | ALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL6015793 | 0.74 | KMT2A (0.46) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL6015920 | 0.74 | ALDH1A1 (0.39) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL6015714 | 0.72 | HTR6 (0.58) | KMT2AALDH1A1MEN1HTTLMNA | |
| SCHEMBL6015750 | 0.72 | ALDH1A1 (0.52) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL3871239 | 0.70 | ATM (0.54) | KMT2AALDH1A1MAPTALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |