Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016069 | 0.99 | KMT2A (0.64) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6015749 | 0.90 | KMT2A (0.51) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6015634 | 0.89 | KMT2A (0.49) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6015996 | 0.89 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6015793 | 0.82 | KMT2A (0.46) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL1413908 | 0.77 | KMT2A (1.00) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6015887 | 0.75 | LMNA (0.59) | ALDH1A1LMNASMN1; SMN2HTTCYP2D6 | |
| SCHEMBL6015920 | 0.74 | ALDH1A1 (0.39) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6015775 | 0.73 | LMNA (0.61) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL3871239 | 0.72 | ATM (0.54) | KMT2AALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |