Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.31 |
| ▸ | CDK1 | P06493 | 4/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229906 | 0.77 | TSHR (0.44) | ALDH1A1TSHR | |
| SCHEMBL9581979 | 0.77 | — | — | |
| SCHEMBL2948314 | 0.76 | KDM4E (0.38) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6015686 | 0.76 | USP2 (0.35) | UPP1RECQLUSP2PNPTSHR | |
| SCHEMBL7093719 | 0.75 | CNR1 (0.38) | — | |
| SCHEMBL2946816 | 0.73 | CNR2 (0.39) | — | |
| SCHEMBL6229846 | 0.73 | ALDH1A1 (0.39) | ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL3865988 | 0.70 | TDP1 (0.31) | — | |
| SCHEMBL5497340 | 0.70 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1NPSR1HBB | |
| SCHEMBL17956195 | 0.69 | LTA4H (0.42) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |