Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289074 | 0.80 | DAO (0.41) | ALDH1A1GAAKDM4ETDP1HTT | |
| SCHEMBL5483907 | 0.76 | TSHR (0.63) | TSHRNPC1RAB9ABCHEACHE | |
| SCHEMBL9582189 | 0.75 | KEAP1 (0.44) | TSHRALDH1A1KDM4ETDP1HPGD | |
| SCHEMBL6015939 | 0.72 | NPC1 (0.49) | TSHRNPC1RAB9AALDH1A1TRPM8 | |
| SCHEMBL6015855 | 0.71 | TSHR (0.40) | TSHRNPC1RAB9ABCHEACHE | |
| SCHEMBL6015979 | 0.70 | SMN1; SMN2 (0.39) | NPC1RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL5480477 | 0.69 | TSHR (0.53) | TSHRBCHEACHEALDH1A1KDM4E | |
| SCHEMBL7604313 | 0.69 | TSHR (0.53) | TSHRNPC1RAB9ABCHEACHE | |
| SCHEMBL5480473 | 0.69 | TSHR (0.53) | TSHRBCHEACHEALDH1A1KDM4E | |
| SCHEMBL7604319 | 0.69 | TSHR (0.52) | TSHRBCHEACHEALDH1A1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |