Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015762 | 1.00 | HTR3A (0.41) | HTR3ACYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL6016047 | 0.99 | HTR3A (0.39) | HTR3ACYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL6015678 | 0.85 | HTR3A (0.56) | HTR3ACYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL6015966 | 0.84 | HTR3A (0.54) | HTR3ACYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL6015845 | 0.82 | KDM4E (0.31) | HPGDALDH1A1KDM4E | |
| SCHEMBL6015931 | 0.77 | KMT2A (0.54) | CYP1A2CYP2D6CYP2C9HPGDALDH1A1 | |
| SCHEMBL7620089 | 0.76 | HTR3A (0.34) | HTR3AHPGDALDH1A1MAOBKDM4E | |
| SCHEMBL6015894 | 0.76 | ALDH1A1 (0.42) | CYP2D6HPGDALDH1A1KDM4EKMT2A | |
| SCHEMBL6016044 | 0.75 | SLC6A3 (0.34) | HTR3AHPGDALDH1A1MAOBPARP1 | |
| SCHEMBL6015766 | 0.75 | ALDH1A1 (0.43) | CYP2C9HPGDALDH1A1MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |