Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016044 | 0.99 | SLC6A3 (0.34) | HTR3ACHEK2SLC6A3SLC6A4PSMB1 | |
| SCHEMBL6015678 | 0.77 | HTR3A (0.56) | HTR3AALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL6015762 | 0.76 | HTR3A (0.41) | HTR3AALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL6015948 | 0.76 | HTR3A (0.41) | HTR3AALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL6015931 | 0.76 | KMT2A (0.54) | HRH3ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL6015966 | 0.76 | HTR3A (0.54) | HTR3AALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL6016047 | 0.75 | HTR3A (0.39) | HTR3AALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL6015825 | 0.72 | SPIN1 (0.48) | HRH3L3MBTL1 | |
| SCHEMBL6015694 | 0.70 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDHTTDRD3 | |
| SCHEMBL6015766 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |