Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878232 | 0.71 | NPC1 (0.33) | KMT2A | |
| SCHEMBL6015962 | 0.70 | NTRK1 (0.62) | MAPTALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL21375011 | 0.69 | L3MBTL1 (0.53) | L3MBTL1GSK3BMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2205076 | 0.69 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL2205080 | 0.69 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL10600278 | 0.65 | KMT2A (0.55) | L3MBTL1MAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29515520 | 0.64 | MAOA (0.45) | L3MBTL1MAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9006406 | 0.63 | L3MBTL1 (0.46) | L3MBTL1GSK3BMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14253822 | 0.62 | MEN1 (0.36) | L3MBTL1MAPTALDH1A1TDP1POLB | |
| SCHEMBL29729466 | 0.62 | GAA (0.41) | L3MBTL1MAPTALDH1A1TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |