Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015994 | 0.71 | L3MBTL1 (0.36) | KMT2A | |
| SCHEMBL6015962 | 0.68 | NTRK1 (0.62) | NPC1MEN1KMT2AFLT3 | |
| SCHEMBL1076557 | 0.68 | ALDH1A1 (0.41) | — | |
| SCHEMBL5656918 | 0.65 | MEN1 (0.32) | NPC1MEN1KMT2A | |
| SCHEMBL6016053 | 0.64 | CHEK1 (0.66) | KMT2AFLT3 | |
| SCHEMBL10755182 | 0.63 | — | — | |
| SCHEMBL666673 | 0.63 | DPP4 (0.33) | — | |
| SCHEMBL4975646 | 0.62 | KDM4E (0.42) | MEN1KMT2A | |
| SCHEMBL11585770 | 0.61 | ADORA2A (0.50) | NPC1MEN1KMT2A | |
| SCHEMBL170429 | 0.59 | ALDH1A1 (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595685-A | Pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-06-17 | — | — | US | disclosed |